Staphylococcus aureus induces cell-surface expression of immune stimulatory NKG2D ligands on human monocytes
Maiken Mellergaard, Rikke Illum Høgh, Astrid Lund, Blanca I. Aldana, Romain Guérillot, Sofie Hedlund Møller, Ashleigh S. Hayes, Nafsika Panagiotopoulou, Zofija Frimand, Stine Dam Jepsen, Camilla Hartmann Friis Hansen, Lars Andresen, Anders Rhod Larsen, Anton Y. Peleg, Timothy P. Stinear, Benjamin P. Howden, Helle S. Waagepetersen, Dorte Frees, Søren Skov
Abstract
suggests that targeting the NKG2D pathway holds potential for managing persistent staphylococcal infections.
Topics & Concepts
Staphylococcus aureusImmune systemNKG2DMicrobiologyMonocyteChemistryCellBacteriaBiologyCytotoxicityImmunologyBiochemistryIn vitroGeneticsImmune Cell Function and InteractionImmune Response and InflammationAntimicrobial Peptides and Activities