Inhibition of NK1R attenuates LPS-induced microglial inflammation and consequent death of PC12 cells
Weifeng Jiang, Xiaoying Wang, Wei Wang, Fang Hua, Zunsheng Zhang, Zuohui Zhang, Jie Xiang, Xin Yang
Topics & Concepts
MicrogliaNeuroinflammationTachykinin receptor 1Cell biologyTumor necrosis factor alphaNeurotoxicityNitric oxide synthasePharmacologyMAPK/ERK pathwayChemistryNitric oxideSubstance PInflammationSignal transductionBiologyReceptorImmunologyInternal medicineEndocrinologyMedicineNeuropeptideBiochemistryToxicityNeuroinflammation and Neurodegeneration MechanismsNeuropeptides and Animal PhysiologySignaling Pathways in Disease