Intracellular persister: A stealth agent recalcitrant to antibiotics
Nicolas Personnic, Patricia Doublet, Sophie Jarraud
Abstract
The bulk of bacteria transiently evading appropriate antibiotic regimes and recovered from non-resolutive infections are commonly refer to as persisters. In this mini-review, we discuss how antibiotic persisters stem from the interplay between the pathogen and the cellular defenses mechanisms and its underlying heterogeneity.
Topics & Concepts
AntibioticsIntracellularMicrobiologyPathogenBiologyBacteriaMultidrug toleranceIntracellular parasiteBiofilmCell biologyGeneticsAntibiotic Resistance in BacteriaBacterial Genetics and BiotechnologyVibrio bacteria research studies