A chalcone-based fluorescent responsive probe for selective detection of nitroreductase activity in bacteria
Sirilak Wangngae, Thitima Pewklang, Kantapat Chansaenpak, Phongsakorn Ganta, Suphanida Worakaensai, Kittipan Siwawannapong, Surayut Kluaiphanngam, Nawarat Nantapong, Rung‐Yi Lai, Anyanee Kamkaew
Abstract
A new chalcone-based fluorescent turn-on probe (<bold>3c</bold>) responsive to nitroreductase (NTR) activity and its application toward the detection of bacteria are presented.
Topics & Concepts
NitroreductaseChemistryChalconeFluorescenceBacteriaBiochemistryBiophysicsCombinatorial chemistryStereochemistryEnzymePhysicsGeneticsQuantum mechanicsBiologyAdvanced biosensing and bioanalysis techniquesMolecular Sensors and Ion DetectionClick Chemistry and Applications