Defining the scope of the European Antimicrobial Resistance Surveillance network in Veterinary medicine (EARS-Vet): a bottom-up and One Health approach
Rodolphe Mader, EU-JAMRAI, Cindy Demay, Evelyne Jouvin‐Marche, Marie-Cécile Ploy, Olivier Barraud, Sadika Bernard, Yohann Lacotte, C. Pulcini, Jérôme Weinbach, Christine Berling, Marielle Bouqueau, Anton Hlava, Claudia Habl, Eva Kernstock, Reinhild Strauß, R Muchl, V Buhmann, Ann Versporten, Anne Ingenbleek, Eline Vandael, Greet Haelterman, Lieven De Raedt, Blaženka Hunjak, Bojana Raičković, Barbora Macková, Eva Niklova, Helena Žemličková, Lucia Hrivňáková, Vlastimil Jindrák, Brian Kristensen, Mikkel Lyndrup, Sissel Skovgaard, Ute Wolf Sönksen, Birgit Aasmäe, Jüri Ruut, Ljudmila Linnik, Olga Sadikova, Pille Märtin, A Zanuzdana, Gülay Kizilkaya-Güneser, Nadiya Oezcelik, Tim Eckmanns, Ageliki Lambrou, Flora Kontopidou, Maria Papadaki, Mariana Tsana, Nikos Maroulis, Alkiviadis Vatopoulos, Emmanouel Papadogiannakis, Marietta Kontarini, Achilleas Gikas, Aimilia Magkanaraki, Alessandra Cozza, Domenico Martinelli, Francesca Fortunato, Rosa Prato, Anna Maria Marella, Annalisa Pantosti, Francesca Prestinaci, Luca Busani, Patrizio Pezzoti, Roberta Creti, Rosa Maria Martoccia, Silvio Brusaferro, Aija Vilde, Aiva Jakovela, Elina Langusa, Liga Grudule, Madara Grinsteine, Uga Dumpis, Asta Dambrauskienė, Astra Vitkauskienė, Daiva Tirvaitė, Lukas Cemnalianskis, Edita Kazėnaitė, Ilma Lozoraitiene, Ruta Adomaitiene, Ruta Ambrazaitiene, Silvija Kiveryte, Agniete Maciulaityte, Jolanta Kuklytė, Justė Petrene, Rolanda Valintėlienė, Virginija Kanapeckienė, Asta Razmiene, Brigita Kairienė, Giedre Aleksiene, Ginreta Valinciute, Robertas Petraitis, Arjen Elsemulder, Ashna Nakched, Jasper Claessen, Lili Gui, Marcel de Kort, Rosa Perán, Alieke Van Leeuwen, Elma Smeets, M.G. Mennen, Pita Spruijt
Abstract
BACKGROUND: Building the European Antimicrobial Resistance Surveillance network in Veterinary medicine (EARS-Vet) was proposed to strengthen the European One Health antimicrobial resistance (AMR) surveillance approach. OBJECTIVES: To define the combinations of animal species/production types/age categories/bacterial species/specimens/antimicrobials to be monitored in EARS-Vet. METHODS: The EARS-Vet scope was defined by consensus between 26 European experts. Decisions were guided by a survey of the combinations that are relevant and feasible to monitor in diseased animals in 13 European countries (bottom-up approach). Experts also considered the One Health approach and the need for EARS-Vet to complement existing European AMR monitoring systems coordinated by the ECDC and the European Food Safety Authority (EFSA). RESULTS: EARS-Vet plans to monitor AMR in six animal species [cattle, swine, chickens (broilers and laying hens), turkeys, cats and dogs], for 11 bacterial species (Escherichia coli, Klebsiella pneumoniae, Mannheimia haemolytica, Pasteurella multocida, Actinobacillus pleuropneumoniae, Staphylococcus aureus, Staphylococcus pseudintermedius, Staphylococcus hyicus, Streptococcus uberis, Streptococcus dysgalactiae and Streptococcus suis). Relevant antimicrobials for their treatment were selected (e.g. tetracyclines) and complemented with antimicrobials of more specific public health interest (e.g. carbapenems). Molecular data detecting the presence of ESBLs, AmpC cephalosporinases and methicillin resistance shall be collected too. CONCLUSIONS: A preliminary EARS-Vet scope was defined, with the potential to fill important AMR monitoring gaps in the animal sector in Europe. It should be reviewed and expanded as the epidemiology of AMR changes, more countries participate and national monitoring capacities improve.