Gut microbial β-glucuronidases regulate host luminal proteases and are depleted in irritable bowel syndrome
Adam Edwinson, Lu Yang, Stéphanie Peters, Nikita Hanning, Patricio Jeraldo, Pratik Jagtap, Joshua B. Simpson, Tzu-Yi Yang, Praveen Kumar, Subina Mehta, Asha Nair, Margaret K. Breen‐Lyles, Lakshmikanth L. Chikkamenahalli, Rondell P. Graham, Benedicte Y. De Winter, Robin Patel, Surendra Dasari, Purna Kashyap, Timothy J. Griffin, Jun Chen, Gianrico Farrugia, Matthew R. Redinbo, Madhusudan Grover
Topics & Concepts
ProteasesProteolytic enzymesGut floraBiologyIrritable bowel syndromeMicrobiologyProteaseMicrobiomeBacteroidesBiochemistryEnzymeBacteriaInternal medicineMedicineBioinformaticsGeneticsGut microbiota and healthGastrointestinal motility and disordersClostridium difficile and Clostridium perfringens research