Idarubicin/mithramycin-acridine orange combination drugs co-loaded by DNA nanostructures: Different effects of intercalation and groove binding on drug release and cytotoxicity
Danfeng Wang, Min Liu, Yushu Wu, Tianxin Weng, Lu Wang, Yongfang Zhang, Yanna Zhao, Jun Han
Topics & Concepts
Acridine orangeIsothermal titration calorimetryCytotoxicityChemistryBinding constantEthidium bromideIntercalation (chemistry)BiophysicsRhodamine 123DNAIn vitroMultiple drug resistanceBiochemistryBinding siteApoptosisBiologyOrganic chemistryAntibioticsAdvanced biosensing and bioanalysis techniquesNanoparticle-Based Drug DeliveryRNA Interference and Gene Delivery