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Photodegradation of carbonic anhydrase IX<i>via</i>a binding-enhanced ruthenium-based photosensitizer

Hao Liang, Jie Wang, Zhengyin Pan, Zong‐Wan Mao, Cai-Ping Tan

2022Chemical Communications14 citationsDOI

Abstract

and in living cells, which significantly inhibits its catalytic activity. The protein photodegradation method may provide new strategies for the development of tools for protein functional studies.

Topics & Concepts

PhotosensitizerRutheniumChemistryMoietyPhotodegradationIn vitroPhotodynamic therapyCatalysisProtoporphyrin IXPhotochemistryCombinatorial chemistryStereochemistryBiochemistryOrganic chemistryPhotocatalysisEnzyme function and inhibitionSynthesis and Catalytic ReactionsAdenosine and Purinergic Signaling
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