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Ligand recognition and allosteric modulation of the human MRGPRX1 receptor

Yongfeng Liu, Can Cao, Xi‐Ping Huang, Ryan H. Gumpper, Moira Rachman, Shih SL, B. Krumm, Shicheng Zhang, Brian K. Shoichet, Jonathan F. Fay, Bryan L. Roth

2022Nature Chemical Biology43 citationsDOI

Topics & Concepts

Allosteric regulationAllosteric modulatorAgonistChemistryReceptorOpioid receptorLigand (biochemistry)OpioidCell biologyBiophysicsNeurosciencePharmacologyBiochemistryBiologyReceptor Mechanisms and SignalingNeuropeptides and Animal PhysiologyNeurobiology and Insect Physiology Research
Ligand recognition and allosteric modulation of the human MRGPRX1 receptor | Litcius