Protective effect of (+)–catechin against lipopolysaccharide-induced inflammatory response in RAW 264.7 cells through downregulation of NF-κB and p38 MAPK
M.A. Sunil, V.S. Sunitha, Prasanthkumar Santhakumaran, Mohind C. Mohan, Midhun Sebastian Jose, E. K. Radhakrishnan, Jyothis Mathew
Topics & Concepts
Tumor necrosis factor alphap38 mitogen-activated protein kinasesChemistryLipopolysaccharideCatechinMAPK/ERK pathwayNitric oxide synthasePharmacologyNitric oxideNF-κBBiochemistryKinaseImmunologyBiologyPolyphenolSignal transductionEnzymeAntioxidantOrganic chemistryTea Polyphenols and EffectsBioactive Compounds and Antitumor AgentsBioactive Compounds in Plants