Synthesis and biological evaluation of novel [1,2,3]triazolo-pyrrolo[1,2-a]pyrido[4,3-d]pyrimidines as EGFR targeting anticancer agents
Sandhya Rani Bandi, Natte Kavitha, Satheesh Kumar Nukala, Narasimha Swamy Thirukovela, Ravinder Manchal, Rambabu Palabindela, Sirassu Narsimha
Topics & Concepts
ChemistryErlotinibStereochemistryIn silicoEGFR inhibitorsMoietyIn vitroCombinatorial chemistryEpidermal growth factor receptorBiochemistryReceptorGeneSynthesis and biological activityClick Chemistry and ApplicationsCancer therapeutics and mechanisms