Synergistic bactericidal activity of a naturally isolated phage and ampicillin against urinary tract infecting <i>Escherichia coli</i> O157.
Zahra Moradpour, Nesa Yousefi, Dorna Sadeghi, Abdollah Ghasemian
Abstract
OBJECTIVES: O157. MATERIALS AND METHODS: O157 was evaluated. RESULTS: O157, while the bacteriophage and combination treatment stopped the proliferation of bacteria from the beginning, and this can compensate the delayed onset of antibiotic action. CONCLUSION: The synergistic action of bacteriophages and antibiotics is an alternative that cannot only be effective against bacterial infections but also contribute to the reduction of antibiotic resistance.
Topics & Concepts
MicrobiologyAmpicillinBacteriophageEscherichia coliAntibioticsPhage therapyAntibiotic resistanceBacteriaBiologyAntimicrobialGeneGeneticsBacteriophages and microbial interactionsEscherichia coli research studiesBacterial Genetics and Biotechnology