Litcius/Paper detail

Malignant adenomyoepithelioma of the breast

Eisa Lari, Ali Lari, Talal Alsaeed

2020International Journal of Surgery Case Reports17 citationsDOIOpen Access PDF

Abstract

INTRODUCTION: Malignant breast adenomyoepithelioma (AME) is a rare subtype of breast cancer. AME is mostly a benign disease that uncommonly undergoes malignant transformation. PRESENTATION OF CASE: Here we present a case of a young, previously healthy female who initially presented with a painless breast lump. The patient underwent wide local excision for atypical cells with squamous metaplasia by core biopsy, but final histopathology showed AME with carcinoma. Thus, a mastectomy and a sentinel lymph node biopsy was undertaken. The patient had an uneventful recovery and no recurrence after the second surgery. DISCUSSION AND CONCLUSION: Malignant transformation of adenomyoepithelioma is reported in a small number of cases. Benign AME may be treated with wide local excision as recurrence is rare locally. Whereas malignant AME tends to be treated with simple mastectomy with or without lymph node biopsy.

Topics & Concepts

MedicineBiopsyWide local excisionMalignant transformationMastectomyHistopathologyBreast cancerLymph nodeSentinel lymph nodeMetaplasiaSquamous metaplasiaRadiologySurgeryCancerPathologyInternal medicineEpitheliumBreast Lesions and CarcinomasBreast Cancer Treatment StudiesMale Breast Health Studies