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Ketamine relieves depression-like behaviors induced by chronic postsurgical pain in rats through anti-inflammatory, anti-oxidant effects and regulating BDNF expression

Yi Yang, Yuxiang Song, Xuan Zhang, Weixing Zhao, Tao Ma, Yi Liu, Penglei Ma, Yifan Zhao, Hong Zhang

2020Psychopharmacology35 citationsDOI

Topics & Concepts

Proinflammatory cytokineBehavioural despair testKetamineMalondialdehydeOxidative stressMedicineNeurotrophic factorsBrain-derived neurotrophic factorInternal medicinePharmacologyHyperalgesiaEndocrinologyAnesthesiaAntidepressantHippocampusInflammationNociceptionReceptorTreatment of Major DepressionTryptophan and brain disordersAnesthesia and Neurotoxicity Research
Ketamine relieves depression-like behaviors induced by chronic postsurgical pain in rats through anti-inflammatory, anti-oxidant effects and regulating BDNF expression | Litcius