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Discovery of a novel small-molecule inhibitor of Fam20C that induces apoptosis and inhibits migration in triple negative breast cancer

Rongyan Zhao, Leilei Fu, Zhaoxin Yuan, Yi Liu, Kai Zhang, Yanmei Chen, Leiming Wang, Dejuan Sun, Lixia Chen, Bo Liu, Lan Zhang

2020European Journal of Medicinal Chemistry31 citationsDOIOpen Access PDF

Topics & Concepts

ChemistryApoptosisIn silicoSmall moleculeDocking (animal)Cancer researchKinaseCancer cellTriple-negative breast cancerEnzymeCell biologyBiochemistryCancerBreast cancerBiologyMedicineNursingGeneticsGeneRetinoids in leukemia and cellular processesUbiquitin and proteasome pathwaysPhytase and its Applications
Discovery of a novel small-molecule inhibitor of Fam20C that induces apoptosis and inhibits migration in triple negative breast cancer | Litcius