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Antigen Presentation by B Cells in Multiple Sclerosis

Scott S. Zamvil, Stephen L. Hauser

2021New England Journal of Medicine43 citationsDOIOpen Access PDF

Abstract

A recent study of a class of HLA molecules on the surface of B cells in persons with multiple sclerosis revealed that many of these HLA molecules present self-peptides to T cells.

Topics & Concepts

Multiple sclerosisHuman leukocyte antigenMedicineAntigen presentationAntigenImmunologyPresentation (obstetrics)Immune systemT cellRadiologyMultiple Sclerosis Research StudiesImmunotherapy and Immune ResponsesT-cell and B-cell Immunology
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