Great debate: default duration of dual antiplatelet treatment after percutaneous coronary intervention in acute coronary syndrome should be 12 months
Robert A Byrne, Marco Valgimigli, Deepak L. Bhatt, J J Coughlan, C. Michael Gibson, Xavier Rosselló, Diana A Gorog, Borja Ibáñez, Stefan James, Antonio Landi, Philippe Gabríel Steg, Gregg W. Stone, Felicita Andreotti
Abstract
Default duration of dual antiplatelet therapy after percutaneous coronary intervention in acute coronary syndrome patients. The main arguments favouring a 12-month default duration (left) are balanced against those favouring a shorter default duration (right). ACS, acute coronary syndromes; CCS, chronic coronary syndromes; CURE, Clopidogrel in Unstable angina to prevent Recurrent Events; DAPT, dual antiplatelet therapy; HBR, high bleeding risk; NSTE, non-ST-elevation; PCI, percutaneous coronary intervention; PLATO, PLAtelet inhibiTion and patient Outcomes; SAPT, single antiplatelet therapy; STEMI, ST-elevation myocardial infarction; TRITON, TRial to assess Improvement in Therapeutic Outcomes by optimizing platelet iNhibition with prasugrel. Central image modified from https://www.vexels.com/png-svg/preview/298671.