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Sequential Organ Failure Assessment (SOFA) Score and Mortality Prediction in Patients With Severe Respiratory Distress Secondary to COVID-19

Mohamed Fayed, Nimesh Patel, Santhalakshmi Angappan, Katherine Nowak, Felipe Vasconcelos Torres, Donald H. Penning, Anoop Chhina

2022Cureus39 citationsDOIOpen Access PDF

Abstract

) to the fraction of inspired oxygen, Glasgow Coma Scale (GCS) score, mean arterial pressure, serum creatinine level, bilirubin level, and platelet count) as well as inpatient mortality. Results There were 320 patients; out of these, 111 were intubated. The receiver operating characteristic (ROC) curve for SOFA at the moment of inclusion in the study had an area under the curve of 0.883. The optimal point for discrimination between mortality and survival is SOFA of 5. A SOFA score of less than two is associated with 100% survival, while a score of more than 11 is associated with 100% mortality. Conclusions SOFA score in COVID-19 patients with severe respiratory distress strongly correlates with the initial SOFA score. It is a valuable tool for predicting mortality in COVID-19 patients.

Topics & Concepts

MedicineSOFA scoreFraction of inspired oxygenInternal medicineReceiver operating characteristicRespiratory failurePneumoniaCoronary artery diseaseMechanical ventilationIntensive care unitCOVID-19 Clinical Research StudiesLong-Term Effects of COVID-19Respiratory Support and Mechanisms
Sequential Organ Failure Assessment (SOFA) Score and Mortality Prediction in Patients With Severe Respiratory Distress Secondary to COVID-19 | Litcius