Bariatric surgery reveals a gut-restricted TGR5 agonist with anti-diabetic effects
Snehal N. Chaudhari, David A. Harris, Hassan Aliakbarian, James Luo, Matthew T. Henke, Renuka Subramaniam, Ashley H. Vernon, Ali Tavakkoli, Eric G. Sheu, A. Sloan Devlin
Topics & Concepts
G protein-coupled bile acid receptorAgonistBile acidIncretinFGF19EndogenyInternal medicineSleeve gastrectomyReceptorCholic acidGastrointestinal tractEndocrinologyGlucagon-like peptide-1HormoneExenatideChemistryType 2 diabetesMedicineDiabetes mellitusObesityWeight lossFibroblast growth factorGastric bypassDiabetes Treatment and ManagementDrug Transport and Resistance MechanismsDiet and metabolism studies