Anticholinergic burden (prognostic factor) for prediction of dementia or cognitive decline in older adults with no known cognitive syndrome

Abstract

This is a protocol for a Cochrane Review (Prognosis). The objectives are as follows:
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\nPrimary objective: to assess whether ACB in older adults is a prognostic factor for future cognitive decline or dementia.
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\nSecondary objective(s): to assess whether ACB is a prognostic factor for older adults recruited in primary care, secondary care, or community settings (with setting used as the basis for subgroup analyses); whether ACB is associated with mortality; to compare the prognostic validity of respective ACB scales; and to examine the effect of duration of exposure and duration of follow‐up on the ACB‐dementia risk association.

Topics & Concepts