Inhibition of the uric acid efflux transporter ABCG2 enhances stimulating effect of soluble uric acid on IL-1β production in murine macrophage-like J774.1 cells
Tomomi Notsu, Yasutaka Kurata, Haruaki Ninomiya, Fikri Taufiq, Koji Komatsu, Junichiro Miake, Tatsuya Sawano, Motokazu Tsuneto, Yasuaki Shirayoshi, Ichiro Hisatome
Topics & Concepts
InflammasomeChemistryAbcg2Uric acidIntracellularCaspase 1Cell cultureBiochemistryPharmacologyTransporterMolecular biologyATP-binding cassette transporterBiologyGeneReceptorGeneticsGout, Hyperuricemia, Uric AcidInflammasome and immune disordersPeroxisome Proliferator-Activated Receptors