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Urinary detection of early responses to checkpoint blockade and of resistance to it via protease-cleaved antibody-conjugated sensors

Quoc D. Mac, Anirudh Sivakumar, Hathaichanok Phuengkham, Congmin Xu, J. Richard Bowen, Fang‐Yi Su, Samuel Z. Stentz, Hyoungjun Sim, Adrian M. Harris, Tonia T. Li, Peng Qiu, Gabriel A. Kwong

2022Nature Biomedical Engineering32 citationsDOIOpen Access PDF

Topics & Concepts

ProteasesProteaseImmune checkpointBlockadeImmune systemCancer researchAntibodyCancerImmunotherapyBiologyMedicineImmunologyEnzymeBiochemistryInternal medicineReceptorCancer Immunotherapy and BiomarkersCAR-T cell therapy researchPeptidase Inhibition and Analysis
Urinary detection of early responses to checkpoint blockade and of resistance to it via protease-cleaved antibody-conjugated sensors | Litcius