Mycobacterium abscessus Opsonization Allows an Escape from the Defensin Bactericidal Action in <i>Drosophila</i>
Hamadoun I. Touré, Nicolas Durand, Isabelle Guénal, Jean‐Louis Herrmann, Fabienne Girard‐Misguich, Sébastien Szuplewski
Abstract
approaches, we show that Defensin is able to control extracellular M. abscessus infection through a direct bactericidal action. In conclusion, we report that M. abscessus escapes the host AMP-mediated humoral response by taking advantage of its internalization by the phagocytes.
Topics & Concepts
Mycobacterium abscessusMicrobiologyAntibody opsonizationBiologyNontuberculous mycobacteriaInnate immune systemDefensinAntimicrobial peptidesImmunologyMycobacteriumImmune systemAntimicrobialBacteriaOpsoninGeneticsPhagocytosisInvertebrate Immune Response MechanismsInsect symbiosis and bacterial influencesAquaculture disease management and microbiota