Differences in Coformer Interactions of the 2,4-Diaminopyrimidines Pyrimethamine and Trimethoprim
Lamis Alaa Eldin Refat, Ciarán O’Malley, John M. Simmie, Patrick McArdle, Andrea Erxleben
Abstract
) salt. Finally, two three-component tmp/sulfa drug/carboxylate cocrystals with a unique ternary synthon are described.
Topics & Concepts
SynthonCocrystalChemistryCrystal engineeringOxalic acidStereochemistryCombinatorial chemistrySupramolecular chemistrySalt (chemistry)Hydrogen bondCrystal structureMoleculeCrystallographyOrganic chemistryCrystallography and molecular interactionsCrystal structures of chemical compoundsCrystallization and Solubility Studies