Disaccharide trehalose in experimental therapies for neurodegenerative disorders: Molecular targets and translational potential
А. Б. Пупышев, T. P. Klyushnik, Anna A. Akopyan, Sandeep Kumar Singh, М. А. Тихонова
Topics & Concepts
AutophagyTrehaloseTFEBNeuroprotectionNeurodegenerationPI3K/AKT/mTOR pathwayAutophagosomeChemical chaperoneMechanistic target of rapamycinProtein aggregationChemistryPharmacologyBiochemistryCell biologyBiologySignal transductionMedicineUnfolded protein responseInternal medicineEndoplasmic reticulumApoptosisDiseaseAutophagy in Disease and TherapyEndoplasmic Reticulum Stress and DiseaseParkinson's Disease Mechanisms and Treatments