A general approach to identify cell-permeable and synthetic anti-CRISPR small molecules
Donghyun Lim, Qingxuan Zhou, Kurt J. Cox, Benjamin K. Law, Miseon Lee, Praveen Kokkonda, Vedagopuram Sreekanth, Rajaiah Pergu, Santosh Kumar Chaudhary, Soumyashree A. Gangopadhyay, Basudeb Maji, Sophia Lai, Yuka Amako, David B. Thompson, Hari K. K. Subramanian, Michael F. Mesleh, Vlado Dančík, Paul A. Clemons, Bridget K. Wagner, Christina M. Woo, George M. Church, Amit Choudhary
Topics & Concepts
NucleaseCRISPRSmall moleculeFörster resonance energy transferComputational biologyBiologyHigh-throughput screeningGenome editingDNACas9ChemistryCell biologyBiochemistryGeneFluorescenceQuantum mechanicsPhysicsCRISPR and Genetic EngineeringAdvanced biosensing and bioanalysis techniquesPlant Virus Research Studies