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Inhibition of PAI-1 Blocks PD-L1 Endocytosis and Improves the Response of Melanoma Cells to Immune Checkpoint Blockade

Yu‐Ju Tseng, Chih‐Hung Lee, Wei‐Yu Chen, Jenq‐Lin Yang, Hong‐Tai Tzeng

2021Journal of Investigative Dermatology37 citationsDOI

Topics & Concepts

BlockadeEndocytosisImmune checkpointMelanomaImmune systemCancer researchImmunologyMedicineCell biologyChemistryImmunotherapyBiologyReceptorInternal medicineCancer Immunotherapy and BiomarkersImmunotherapy and Immune ResponsesImmune Cell Function and Interaction
Inhibition of PAI-1 Blocks PD-L1 Endocytosis and Improves the Response of Melanoma Cells to Immune Checkpoint Blockade | Litcius