Optical resolution of 1,16-dihydroxytetraphenylene by chiral gold(<scp>iii</scp>) complexation and its applications as chiral ligands in asymmetric catalysis
Jia Guo, Wen-Bin Xiong, Hao-Ran Ma, Luoyi Fan, You‐Yun Zhou, Henry Ν. C. Wong, Jian‐Fang Cui
Abstract
Chiral gold( iii ) complex was found to be a “golden key” to unlock (±)-1,16-dihydroxytetraphenylene (DHTP), leading to enantiopure DHTP in a large quantity. This approach provided convenient access to 2,15-diaryl ( S )-DHTPs and phosphoramidites.
Topics & Concepts
CatalysisResolution (logic)ChemistryCombinatorial chemistryEnantioselective synthesisOrganic chemistryStereochemistryComputer scienceArtificial intelligenceMolecular spectroscopy and chiralityAxial and Atropisomeric Chirality SynthesisSurface Chemistry and Catalysis