Tissue folding at the organ–meristem boundary results in nuclear compression and chromatin compaction
Kateryna Fal, Niklas Korsbo, Juan Alonso‐Serra, José Teles, Mengying Liu, Yassin Refahi, Marie‐Edith Chabouté, Henrik Jönsson, Olivier Hamant
Abstract
Significance During development, growth deforms tissues and organs. This is notably the case during the formation of new flowers in plants, as the tissue folds during young floral bud emergence. Here, we provide further evidence that organogenesis compresses the cells at the boundary, separating the organ from the stem cell niche, and we show that this leads to nucleus compression and chromatin changes. While mechanical forces are well known to affect nucleus shape and chromatin in mammalian cells in culture, this demonstrates that such an effect also occurs in a developing organism and suggests that forces may help to define boundary domains through large-scale chromatin effects.