A comprehensive pan-cancer analysis on the immunological role and prognostic value of TYMP in human cancers
Yalan Yang, Li Jiang, Sixue Wang, Huan Chen, Mingyu Yi, Yuqing Wu, Zeying Li, Xiaoling Fang
Abstract
The TYMP gene encodes an important nucleoside metabolism enzyme which is a ratelimiting enzyme for chemotherapeutic drug metabolism. Previous studies have shown that TYMP is highly expressed in many different tumors, promoting invasiveness and progression, and that it helps to predict the response to chemotherapeutic drugs. However, the role of TYMP in tumor immunity and prognosis remains largely unclear. The purpose of this pan-cancer analysis was to acquire more data on the function of TYMP function and its clinical significance.
Topics & Concepts
CancerMedicineValue (mathematics)OncologyInternal medicineComputer scienceMachine learningCancer Immunotherapy and BiomarkersFerroptosis and cancer prognosisImmunotherapy and Immune Responses