AcrIF5 specifically targets DNA-bound CRISPR-Cas surveillance complex for inhibition
Yongchao Xie, Laixing Zhang, Zhengyu Gao, Peipei Yin, Hao Wang, Hang Li, Zeliang Chen, Yi Zhang, Maojun Yang, Yue Feng
Topics & Concepts
CRISPRDNATrans-activating crRNAMechanism (biology)BiologySmall moleculeComputational biologyChemistryCas9BiochemistryGenePhilosophyEpistemologyCRISPR and Genetic EngineeringViral Infections and Immunology ResearchRNA and protein synthesis mechanisms