GSDMD drives canonical inflammasome‐induced neutrophil pyroptosis and is dispensable for NETosis
Dhruv Chauhan, Dieter Demon, Lieselotte Vande Walle, Oonagh Paerewijck, Annalisa Zecchin, Leslie Bosseler, Karin Santoni, Rémi Planès, Sílvia Ribó, Amelie Fossoul, Amanda Gonçalves, Hanne Van Gorp, Nina Van Opdenbosch, Filip Van Hauwermeiren, Étienne Meunier, Andy Wullaert, Mohamed Lamkanfi
Topics & Concepts
PyroptosisInflammasomeAIM2NLRC4SecretionPyrin domainCaspase 1Innate immune systemCell biologyNeutrophil extracellular trapsBiologyProgrammed cell deathNALP3InflammationImmunologyChemistryImmune systemApoptosisBiochemistryInflammasome and immune disordersNeutrophil, Myeloperoxidase and Oxidative MechanismsHeme Oxygenase-1 and Carbon Monoxide