Hypoglycemic effects and modulation of gut microbiota of diabetic mice by saponin from<i>Polygonatum sibiricum</i>
Jiayuan Luo, Yangyang Chai, Min Zhao, Qingqi Guo, Yihong Bao
Abstract
) and pyruvate kinase (0.174 ± 0.038 U per g prot). Finally, it was found that PSS could alleviate the symptoms of polyphagia and polydipsia in diabetic mice, regulate the gut microbiota of diabetic mice, increase the number of probiotics, and reduce the number of harmful bacteria. In summary, PSS may play an important role in regulating diabetes and can be developed as a promising natural material for diabetes prevention and treatment.
Topics & Concepts
SaponinTraditional medicineDiabetes mellitusBiologyMedicineEndocrinologyAlternative medicinePathologyPolysaccharides and Plant Cell WallsGinseng Biological Effects and ApplicationsPharmacological Effects of Natural Compounds