Hypomethylation of miR-17-92 cluster in lupus T cells and no significant role for genetic factors in the lupus-associated DNA methylation signature
Patrick Coit, Xiavan Roopnarinesingh, Lourdes Ortiz‐Fernández, Kathleen McKinnon-Maksimowicz, Emily E. Lewis, Joan T. Merrill, W. Joseph McCune, Jonathan D. Wren, Amr H. Sawalha
Topics & Concepts
Systemic lupus erythematosusDNA methylationEpigeneticsIRF7MethylationCpG siteBiologyLupus erythematosusGeneticsImmunologyGenome-wide association studyMolecular biologyGeneMedicineGenotypeGene expressionDiseaseSingle-nucleotide polymorphismInternal medicineAntibodySystemic Lupus Erythematosus Researchinterferon and immune responsesEpigenetics and DNA Methylation