Cyclic AMP represses pathological MEF2 activation by myocyte-specific hypo-phosphorylation of HDAC5
Tao He, Jiale Huang, Lan Chen, Gang Han, David A. Stanmore, Jutta Krebs-Haupenthal, Metin Avkiran, Marco Hagenmüller, Johannes Backs
Topics & Concepts
Mef2PhosphorylationPathologicalCell biologyMyocyteCancer researchHistone deacetylase 5ChemistryInternal medicineEndocrinologyBiologyMedicineTranscription factorAcetylationBiochemistryGeneEnhancerHistone methyltransferaseHistone Deacetylase Inhibitors ResearchPeptidase Inhibition and AnalysisAdenosine and Purinergic Signaling