Acute lymphoblastic leukemia-derived exosome inhibits cytotoxicity of natural killer cells by TGF-β signaling pathway
Huijun Yu, Tingting Huang, Daming Wang, Lei Chen, Xi Lan, Xintong Liu, Keyan Chen, Haihong He, Shaobo Li, Yiwen Zhou, Jiansheng Xie
Topics & Concepts
Jurkat cellsPerforinGranzyme BMicrovesiclesGranzymeCytotoxic T cellK562 cellsBiologyCell biologyCancer researchExosomeInterleukin 12CytotoxicityMolecular biologyChemistryImmunologyT cellLeukemiaImmune systemmicroRNAIn vitroBiochemistryGeneExtracellular vesicles in diseaseImmune Cell Function and InteractionReproductive System and Pregnancy