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Purinergic-associated immune responses in neurodegenerative diseases

Sara Carracedo, Agathe Launay, Paul-Alexandre Déchelle-Marquet, Émilie Faivre, David Blum, Cécile Delarasse, Éric Boué‐Grabot

2024Progress in Neurobiology13 citationsDOIOpen Access PDF

Abstract

R, P2X4 and P2X7 and their possible relevance to specific neurodegenerative disorders. Understanding the molecular mechanisms governing purinergic receptor interaction will be crucial for advancing the development of effective immunotherapies targeting neurodegenerative diseases.

Topics & Concepts

Purinergic receptorPurinergic signallingAmyotrophic lateral sclerosisAdenosineNeuroscienceImmune systemExtracellularAdenosine triphosphateDiseaseAdenosine receptorReceptorBiologyMedicineImmunologyCell biologyInternal medicineEndocrinologyAgonistAdenosine and Purinergic SignalingNeuroinflammation and Neurodegeneration MechanismsNeurological Complications and Syndromes