Molecular determinants of binding of non-oxime bispyridinium nerve agent antidote compounds to the adult muscle nAChR
Max Epstein, Karan Bali, Thomas J. Piggot, A. Christopher Green, Christopher M. Timperley, Mike Bird, John E.H. Tattersall, Isabel Bermúdez, Philip C. Biggin
Topics & Concepts
Allosteric regulationNicotinic acetylcholine receptorNerve agentAntidoteChemistryAcetylcholinesteraseAcetylcholinePharmacologyNeuromuscular junctionNeuromuscular transmissionBiophysicsNeurotransmissionNicotinic agonistBiochemistryNeuroscienceBiologyReceptorEnzymeToxicityEndocrinologyOrganic chemistryInsect and Pesticide ResearchPesticide Exposure and ToxicityNicotinic Acetylcholine Receptors Study