Structure-Guided Engineering of the Homodimeric Mango-IV Fluorescence Turn-on Aptamer Yields an RNA FRET Pair
Robert J. Trachman, Razvan Cojocaru, Di Wu, Grzegorz Piszczek, Michaël Ryckelynck, Peter J. Unrau, A.R. Ferré-D′Amaré
Topics & Concepts
AptamerFörster resonance energy transferRNAFluorophoreFluorescenceBiophysicsChemistrySystematic evolution of ligands by exponential enrichmentBimolecular fluorescence complementationG-quadruplexBiochemistryBiologyDNAMolecular biologyGenePhysicsQuantum mechanicsAdvanced biosensing and bioanalysis techniquesRNA and protein synthesis mechanismsDNA and Nucleic Acid Chemistry