Electrochemical biosensor for the simultaneous determination of rheumatoid factor and anti-cyclic citrullinated peptide antibodies in human serum
Sara Guerrero, Esther Sánchez‐Tirado, Gonzalo Martínez‐García, A. González, Paloma Yáñez‐Sedeño, José M. Pingarrón
Abstract
, respectively. The simultaneous determination can be completed in about two hours using a simple protocol and a sample volume (25 μL) four times smaller than that required by the ELISA method. The dual electrochemical biosensor was used for the determination of both target biomarkers in human serum.
Topics & Concepts
Rheumatoid factorRheumatoid arthritisAutoantibodyAntibodyPeptideBiosensorMedicineAutoimmune diseaseImmunologyChemistryBiochemistryMonoclonal and Polyclonal Antibodies ResearchRheumatoid Arthritis Research and TherapiesSystemic Lupus Erythematosus Research