A novel non-viral delivery method that enables efficient engineering of primary human T cells for ex vivo cell therapy applications
Heather Kavanagh, Susan Dunne, Darren S.D. Martin, Emily J. McFadden, Louise Gallagher, Jessica Schwaber, Siobhán Leonard, Shirley O’Dea
Topics & Concepts
ElectroporationChimeric antigen receptorBiologyGene deliveryTransfectionEx vivoGenetic enhancementImmune systemJurkat cellsCell biologyMolecular biologyT cellCell cultureIn vivoImmunologyGeneGeneticsBiotechnologyBiochemistryCAR-T cell therapy researchMicrobial Inactivation MethodsCRISPR and Genetic Engineering