Pushing the limits of activity and stability: the effects of Lewis acids on non-heme iron–NHC epoxidation catalysts
Florian Dyckhoff, Jonas F. Schlagintweit, Robert M. Reich, Fritz E. Kühn
Abstract
Tetradentate iron–NHC complexes exhibit unprecedented activity (TOF: 410 000 h<sup>−1</sup>) in the epoxidation of <italic>cis</italic>-cyclooctene by addition of Lewis acids.
Topics & Concepts
Lewis acids and basesCycloocteneCatalysisChemistryHemeMedicinal chemistryOrganic chemistryEnzymeMetal-Catalyzed Oxygenation MechanismsCarbon dioxide utilization in catalysisSynthetic Organic Chemistry Methods