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Setd2 determines distinct properties of intestinal ILC3 subsets to regulate intestinal immunity

Jiali Chang, Xiaojuan Ji, Tian Deng, Jinxin Qiu, Zhaoyun Ding, Li Zhao, Yanhui Ma, Xiaoyu Hu, Li Li, Ju Qiu

2022Cell Reports21 citationsDOIOpen Access PDF

Abstract

ILC3s. Therefore, Setd2 determines distinct chromatin status and transcriptomic programs of ILC3 subsets to affect their function and intestinal immunity.

Topics & Concepts

Innate lymphoid cellBiologyImmunologyCell biologyImmunityRegulatory T cellLymphopoiesisImmune systemT cellHaematopoiesisStem cellIL-2 receptorIL-33, ST2, and ILC PathwaysEosinophilic EsophagitisImmune Cell Function and Interaction
Setd2 determines distinct properties of intestinal ILC3 subsets to regulate intestinal immunity | Litcius