Mapping the SARS-CoV-2 spike glycoprotein-derived peptidome presented by HLA class II on dendritic cells
Robert Parker, Thomas Partridge, Catherine Wormald, Rebeca Kawahara, Victoria Stalls, Maria Aggelakopoulou, Jimmy Parker, Rebecca Powell Doherty, Yoanna Ariosa Morejon, Esther Lee, Kevin O. Saunders, Barton F. Haynes, Priyamvada Acharya, Morten Thaysen‐Andersen, Persephone Borrow, Nicola Ternette
Abstract
T cell responses in infected individuals and vaccine recipients and have application in next-generation vaccine design.
Topics & Concepts
Human leukocyte antigenGlycoproteinGlycanBiologyImmunologyGlycosylationImmune systemHLA-DRPeptide vaccinePeptideVirologyAntigenComputational biologyEpitopeGeneticsBiochemistryvaccines and immunoinformatics approachesImmunotherapy and Immune ResponsesSARS-CoV-2 and COVID-19 Research