The Tolerance of Gut Commensal <i>Faecalibacterium</i> to Oxidative Stress Is Strain Dependent and Relies on Detoxifying Enzymes
Tatiana Botin, Luis Ramirez-Chamorro, Jasmina Vidić, Philippe Langella, Isabelle Martin‐Verstraete, Jean‐Marc Chatel, Sandrine Auger
Abstract
Commensal bacteria in the genus Faecalibacterium have been proposed for use as next-generation probiotics, but efforts to cultivate and exploit the potential of these strains have been limited by their sensitivity to O 2 . More broadly, little is known about how commensal and health-associated bacterial species in the human microbiome respond to the oxidative stress that occurs as a result of inflammation in the colon.
Topics & Concepts
Strain (injury)MicrobiologyEnzymeOxidative stressBiologyBacteriaBacterial strainGeneticsBiochemistryAnatomyGut microbiota and healthBiochemical effects in animalsDiet and metabolism studies