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Synthesis of substituted 3,4-dihydroquinazolinones <i>via</i> a metal free Leuckart–Wallach type reaction

Suvarna Bokale-Shivale, Mohammad Al Amin, Rajiv T. Sawant, Marc Y. Stevens, Lewend Turanli, Adam Hallberg, Suresh B. Waghmode, Luke R. Odell

2020RSC Advances12 citationsDOIOpen Access PDF

Abstract

A novel cascade cyclization/Leuckart–Wallach type strategy to prepare biologically important 3,4-dihydroquinazolinones is presented.

Topics & Concepts

Type (biology)ChemistryCombinatorial chemistryMedicinal chemistryGeologyPaleontologyQuinazolinone synthesis and applicationsChemical Synthesis and AnalysisAsymmetric Hydrogenation and Catalysis
Synthesis of substituted 3,4-dihydroquinazolinones <i>via</i> a metal free Leuckart–Wallach type reaction | Litcius