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In-silico and in-vitro investigation of STAT3-PIM1 heterodimeric complex: Its mechanism and inhibition by curcumin for cancer therapeutics

Sutapa Mahata, Santosh Kumar Behera, Sunil Kumar, Pranab Kumar Sahoo, Sinjini Sarkar, Mobashar Hussain Urf Turabe Fazil, Vilas D. Nasare

2022International Journal of Biological Macromolecules17 citationsDOI

Topics & Concepts

PIM1CurcuminChemistryIn silicoSignal transductionBiochemistrySTAT3Cell biologyCancer researchBiologyPhosphorylationGeneSerineCancer Mechanisms and TherapySynthesis and biological activitySynthesis and Characterization of Heterocyclic Compounds
In-silico and in-vitro investigation of STAT3-PIM1 heterodimeric complex: Its mechanism and inhibition by curcumin for cancer therapeutics | Litcius