Targeting metabotropic glutamate receptor 4 for cancer immunotherapy
Zhuoya Wan, Runzi Sun, Yang‐Wuyue Liu, Sihan Li, Jingjing Sun, Jiang Li, Junjie Zhu, Pearl Moharil, Bei Zhang, Pengfei Ren, Guolian Ren, Min Zhang, Xiaochao Ma, Shuang-Shuang Dai, Da Yang, Binfeng Lu, Song Li
Abstract
correlated with improved survival in patients with melanoma. Targeting GRM4 represents a new approach for cancer immunotherapy.
Topics & Concepts
Immune systemImmunotherapyMetabotropic glutamate receptorCancer immunotherapyMetabotropic receptorMetabotropic glutamate receptor 5Glutamate receptorMedicineCancerReceptorCancer researchBiologyImmunologyInternal medicineCancer, Stress, Anesthesia, and Immune ResponseAdenosine and Purinergic SignalingNanoplatforms for cancer theranostics