Per- and polyfluoroalkyl substances (PFAS) exposure might be a risk factor for thyroid cancer
Jing Li, Zhixiong Shi
Abstract
In the November 2023 issue of eBioMedicine, Maaike van Gerwen et al. presented their work “Per- and Polyfluoroalkyl substances (PFAS) Exposure and Thyroid Cancer Risk”, which reports an association between PFAS exposure and thyroid cancer using both a cross-sectional and longitudinal study design.1 The study found a 56% increased rate of thyroid cancer diagnosis per doubling of linear perfluorooctanesulfonic acid (n-PFOS) in plasma; importantly, a similar result was also observed when including papillary thyroid cancer cases only.
Topics & Concepts
Thyroid cancerMedicineCancerThyroidInternal medicinePopulationThyroid functionOverdiagnosisEnvironmental healthEndocrinologyPhysiologyPer- and polyfluoroalkyl substances researchAtmospheric chemistry and aerosolsAir Quality and Health Impacts