A New Pyrroloquinoline-Derivative-Based Fluorescent Probe for the Selective Detection and Cell Imaging of Lysine
Bing Yang, Jiahua Zhou, Xu Huang, Zhongping Chen, Shu Tian, Yujun Shi
Abstract
In this paper, a new pyrroloquinoline-derivative-based fluorescent probe, PQP-1, was prepared for the selective detection of Lys in living cells and natural mineral water for drinking. PQP-1 exhibited high selectivity, low limit of detection, and a wide pH range. PQP-1 could be successfully applied for imaging Lys in living cells and in natural mineral water for drinking. We expect that PQP-1 will expand the detection reaction mechanism and the practical biological applications of Lys.
Topics & Concepts
Detection limitFluorescenceChemistryDerivative (finance)LysineSelectivityLiving cellBiochemistryChromatographyBiologyAmino acidBiological systemCatalysisPhysicsBusinessQuantum mechanicsFinanceMolecular Sensors and Ion DetectionPorphyrin and Phthalocyanine ChemistryLuminescence and Fluorescent Materials